浙江大学求是特聘教授、研究员、博士生导师。美国医学遗传学会临床实验室主任，美国医学遗传学院专家委员。主要科研方向为医学遗传学、转化及临床工作。运用基因组学和生物化学技术，开创了多种遗传疾病的精准诊断和无创产前筛查方法，该方法在大规模人群遗传病筛查和出生缺陷预防方面取得了国际公认的重要成果。通过基因组学技术发现了VPS11、RBM42等新的致病基因，并揭示了这些基因在脑发育中的重要信号通路及作用机制。以第一/通讯作者在Nature Medicine、Cell Discovery、Protein & Cell、Genetics in Medicine等期刊发表了多篇高影响力论文，参编专著2部。主持并参与多项国家重点研发计划项目子课题与国自然科学基金。与团队共同获得上海市科学技术进步一等奖，国家科学技术进步二等奖。

• 1. 国家自然科学基金委员会, 面上项目, Matriptase-3参与介导胚胎胼胝体及早期脑发育的机制研究, 2023-01-01 至 2026-12-31, 50万元, 在研, 主持；
• 2. 国家重点研发计划“儿童神经发育异常的遗传调控研究”；课题：儿童神经发育异常的致病基因发现，2020YFA0804000，课题负责人，2020.12-2025.11，239万，主持；
• 3. 国家自然科学基金委员会面上项目“新型胎儿游离核酸多维整合分析技术揭示染色体非整倍体发生机制与临床应用”，82071661，课题负责人，2021.01-2024.12，59万元，主持；

• 1. Jinglan Zhang#*, Yanting Wu#, Songchang Chen#, Qiong Luo#, Hui Xi#, Jianli Li, Xiaomei Qin, Ying Peng, Na Ma, Bingxin Yang, Xiang Qiu, Weiliang Lu, Yuan Chen, Ying Jiang, Panpan Chen, Yifeng Liu, Chen Zhang, Zhiwei Zhang, Yu Xiong, Jie Shen, Huan Liang, Yunyun Ren, Chunmei Ying, Minyue Dong, Xiaotian Li, Congjian Xu, Hua Wang*, Dan Zhang*, Chenming Xu* & Hefeng Huang*. Prospective prenatal cell-free DNA screening for genetic conditions of heterogenous etiologies.  Nat Med. 2024 Feb;30(2):470-479. PMID: 38253798.
• 2. Yanting Wu#*, Kaizhen Su#, Ying Zhang#, Langchao Liang#, Fei Wang, Siyue Chen, Ling Gao, Qiutong Zheng, Cheng Li, Yunfei Su, Yiting Mao, Simeng Zhu, Chaochao Chai, Qing Lan, Man Zhai, Xin Jin, Jinglan Zhang, Xun Xu, Yu Zhang*, Ya Gao*, Hefeng Huang*. A spatiotemporal transcriptomic atlas of mouse placentation. Cell Discov. 2024 Oct 22;10(1):110. PMID:39438452.
• 3. Yiyao Chen# , Bingxin Yang# , Xiaoyu Merlin Zhang# , Songchang Chen# , Minhui Wang, Liya Hu，Nina Pan, Shuyuan Li, Weihui Shi, Zhenhua Yang, Li Wang, Li Wang, Yajing Tan, Jian Wang, Yanlin Wang, Qinghe Xing, Zhonghua Ma, Jinsong Li, He-Feng Huang*, Jinglan Zhang*, Chenming Xu*. Biallelic Variants in RBM42 cause a multimystem disorder with neurological, facial, cardiac, and musculoskeletal involvement. Protein Cell. 2024 Jan 3; 15(1):52-68. PMID: 37294900.
• 4. Qiong Luo#, Yanting Wu#, Songchang Chen, Chenming Xu, Dan Zhang, Hefeng Huang*, Jinglan Zhang*. Advancing prenatal diagnosis through comprehensive fetal cell-free DNA screening. Clin Transl Med. 2024 Dec; 14(12):e70129. PMID:39710585.
• 5. Chenming Xu#, Jianli Li#, Songchang Chen#, Xiaoqiang Cai#, Ruilin Jing, Xiaomei Qin, Dong Pan, Xin Zhao, Dongyang Ma, Xiufeng Xu, Xiaojun Liu, Can Wang, Bingxin Yang, Lanlan Zhang, Shuyuan Li, Yiyao Chen, Nina Pan, Ping Tang, Jieping Song, Nian Liu, Chen Zhang, Zhiwei Zhang, Xiang Qiu, Weiliang Lu, Chunmei Ying, Xiaotian Li, Chongjian Xu, Yanlin Wang, Yanting Wu*, He-Feng Huang*, Jinglan Zhang*. Genetic deconcolution of fetal and maternal cell-free DNA in maternal plasma enables next-generation non-invasive prenatal screening. Cell Discov. 2022 Oct 13 ;8(1):109. PMID:36229437.
• 6. Jinglan Zhang*, Jianli Li, Jennifer B Saucier, Yanming Feng, Yanjun Jiang, Jefferson Sinson, Anne K McCombs, Eric S Schmitt, Sandra Peacock, Stella Chen, Hongzheng Dai, Xiaoyan Ge, Guoli Wang, Chad A Shaw, Hui Mei, Amy Breman, Fan Xia, Yaping Yang, Anne Purgason, Alan Pourpak, Zhao Chen, Xia Wang, Yue Wang, Shashikant Kulkarni, Kwong Wai Choy, Ronald J Wapner, Ignatia B Van den Veyver, Arthur Beaudet, Sheetal Parmar, Lee-Jun Wong, Christine M Eng. Non-invasive prenatal sequencing for multiple Mendelian monogenic disorders using circulating cell-free fetal DNA. Nat Med. 2019 Mar;25(3):439-447. PMID:30692697.
• 7. Shiyu Luo, C Alexander Valencia, Jinglan Zhang, Ni-Chung Lee, Jesse Slone, Baoheng Gui, Xinjian Wang, Zhuo Li, Sarah Dell, Jenice Brown, Stella Maris Chen, Yin-Hsiu Chien, Wuh-Liang Hwu, Pi-Chuan Fan, Lee-Jun Wong, Paldeep S Atwal, Taosheng Huang*. Biparental Inheritance of Mitochondrial DNA in Humans. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13039-13044. PMID:30478036.
• 8. Girish N Nadkarni, Geneviève Galarneau, Stephen B Ellis, Rajiv Nadukuru, Jinglan Zhang, Stuart A Scott, Claudia Schurmann, Rongling Li, Laura J Rasmussen-Torvic, Abel N Kho, M Geoffrey Hayes, Jennifer A Pacheco, Teri A Manolio, Rex L Chisholm, Dan M Roden, Joshua C Denny, Eimear E Kenny, Erwin P Bottinger*. Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans. J Am Coll Cardiol. 2017 Mar 28;69(12):1564-1574. PMID:28335839.
• 9. Yanming Feng， Xiaoyan Ge， Linyan Meng, Jennifer Scull, Jianli Li, Xia Tian, Tao Zhang, Weihong Jin, Hanyin Cheng, Xia Wang, Mari Tokita, Pengfei Liu, Hui Mei, Yue Wang, Fangyuan Li, Eric S Schmitt , Wei V Zhang, Donna Muzny, Shu Wen, Zhao Chen, Yaping Yang, Arthur L Beaudet, Xiaoming Liu, Christine M Eng, Fan Xia , Lee-Jun Wong, Jinglan Zhang. The next generation of population-based spinal muscular atrophy carrier screening: comprehensive pan-ethnic SMN1 copy-number and sequence variant analysis by massively parallel sequencing. Genet Med. 2017 Aug;19(8):936-944. PMID:28125085.
• 10. Daryl A Scott, Andres Hernandez-Garcia, Mahshid S Azamian, Valerie K Jordan, Bum Jun Kim, Molly Starkovich, Jinglan Zhang, Lee-Jun Wong, Sandra A Darilek, Amy M Breman, Yaping Yang, James R Lupski, Amyn K Jiwani, Bibhuti Das, Seema R Lalani, Alejandro D Iglesias, Jill A Rosenfeld, Fan Xia. Congenital heart defects and left ventricular non-compaction in males with loss-of-function variants in NONO.  J Med Genet. 2017 Jan;54(1):47-53. PMID:27550220.
• 11. Jinglan Zhang#, Véronik Lachance#, Adam Schaffner, Xianting Li, Anastasia Fedick, Lauren E Kaye, Jun Liao, Jill Rosenfeld, Naomi Yachelevich, Mary-Lynn Chu, Wendy G Mitchell, Richard G Boles, Ellen Moran, Mari Tokita, Elizabeth Gorman, Kaytee Bagley, Wei Zhang, Fan Xia, Magalie Leduc, Yaping Yang, Christine Eng, Lee-Jun Wong, Raphael Schiffmann, George A Diaz, Ruth Kornreich, Ryan Thummel, Melissa Wasserstein, Zhenyu Yue, Lisa Edelmann*. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. PLoS Genet. 2016 Apr 27;12(4):e1005848. PMID:27120463.
• 12. Jinglan Zhang, Anastasia Fedick, Stephanie Wasserman, Geping Zhao, Lisa Edelmann, Erwin P Bottinger, Ruth Kornreich, Stuart A Scott. Analytical Validation of a Personalized Medicine APOL1 Genotyping Assay for Nondiabetic Chronic Kidney Disease Risk Assessment. J Mol Diagn. 2016 Mar;18(2):260-6. PMID: 26773863.

• Fedick A.M., Zhang J., Edelmann L., Kornreich R. (2019) Prenatal Diagnosis of Cystic Fibrosis. Methods Mol Biol. 1885:221-231；
• Zhang, J., Chen, H., Kornreich R., Yu, C. (2019) Prenatal Diagnosis of Tay-Sachs Disease. Methods Mol Biol. 1885:233-250；
• Fedick, A., Zhang, J. (2017) Next Generation of Carrier Screening. Next Generation Sequencing Based Clinical Molecular Diagnosis of Human Genetic Disorders, Springer；
• Mei H., Dai H., Zhang J., Wong L.J., Magoulas L.P. (2017) Application of Next-Generation Sequencing in Noonan Spectrum Disorders. Next Generation Sequencing Based Clinical Molecular Diagnosis of Human Genetic Disorders, Springer；

• 2020年，国家科技进步二等奖（发育源性疾病和遗传性出生缺陷的机制研究及临床精准防控 完成人：黄荷凤、徐晨明、金丽、吴琰婷、陈松长、张静澜等）；

• 2019年，海市科技进步一等奖（发育源性疾病和遗传性出生缺陷的机制研究及临床精准防控 完成人：黄荷凤、徐晨明、张静澜等）；

• 2016年，Top rated abstract at ACMG Annual Clinical Genetics Meeting （Title: Population Carrier Screening for Spinal Muscular Atrophy by Next Generation Sequencing）；

• Chinese Government Award for Outstanding Self-financed Students Abroad （国家优秀自费留学生）, 2008, The Government of People’s Republic of China；

• John R. Kelsey Jr. Student Award, 2008, Baylor College Medicine；